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Amantadine

dm+d VMPP - 1107411000001100

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Drug Description

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Amantadine treats parkinsonian dyskinesia as an muscarinic antagonist and acts as a noncompetitive NMDA antagonist. Amantadine was used as an antiviral drug used to treat and prevent influenza A infections. The antiviral mechanism of action is antagonism of the influenza A surface protein M2. M2 inhibition prevents viral shedding. Due to high levels of viral resistance to amantadine and other adamantanes, these drugs are no longer used against influenza A virus.

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