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Donepezil Hydrochloride

dm+d VMPP - 1074711000001100

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Donepezil, sold as the trade name Aricept among others, is a medication used to treat Alzheimer's disease. It appears to result in a small benefit in mental function and ability to function. Use, however, has not been shown to change the progression of the disease. Treatment should be stopped if no benefit is seen. It is taken by mouth.Common side effects include nausea, trouble sleeping, aggression, diarrhea, feeling tired, and muscle cramps. Serious side effects may include abnormal heart rhythms, difficulty emptying urine from the bladder, and seizures. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor.Donepezil was approved for medical use in the United States in 1996. It is available as a generic medication. In the United Kingdom a typical months supply costs the NHS about £8.44 as of 2019. The wholesale cost of this amount in the United States is about US$1.38. In 2016 it was the 98th most prescribed medication in the United States with more than 7 million prescriptions.

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