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Famotidine, sold under the trade name Pepcid among others, is a medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour.Common side effects include headache, intestinal upset, and dizziness. Serious side effects may include pneumonia and seizures. Use in pregnancy appears safe but has not been well studied while use during breastfeeding is not recommended. It is a histamine H2 receptor antagonist.Famotidine was patented in 1979 and came into medical use in 1985. It is available as a generic medication. A month supply in the United Kingdom costs the NHS about 30 ₤ as of 2019. In the United States the wholesale cost of this amount is about 2 USD. In 2016 it was the 125th most prescribed medication in the United States with more than 5 million prescriptions.
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