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Levetiracetam, marketed under the trade name Keppra among others, is a medication used to treat epilepsy. It is used for partial onset, myoclonic, or tonic-clonic seizures. It is taken by mouth as an immediate or extended release formulation or by injection into a vein.Common side effects include sleepiness, dizziness, feeling tired, and aggression. Severe side effects may include psychosis, suicide, and allergic reactions such as Stevens-Johnson syndrome and anaphylaxis. It is unclear if use is safe during pregnancy but it appears okay when breastfeeding. It is the S-enantiomer of etiracetam. How it works is not clear.Levetiracetam was approved for medical use in the United States in 1999. It is available as a generic medication. A month supply in the United Kingdom costs the NHS about £19.31 per month as of 2019. In the United States the wholesale cost of this amount is about US$4.50. In 2016 it was the 89th most prescribed medication in the United States with more than 8 million prescriptions.
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