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Losartan

dm+d VMPP - 9415111000001108

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Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure. It is also used for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used alone or in addition to other blood pressure medication. Up to six weeks may be required for the full effects to occur.Common side effects include muscle cramps, stuffy nose, cough, and high blood potassium. Severe side effects may include angioedema, low blood pressure, and kidney problems. Use during pregnancy may result in harm to the baby. Use is not recommended during breastfeeding. It is in the angiotensin receptor blocker family of medication. It works by blocking angiotensin II.Losartan was patented in 1986 and approved for medical use in the United States in 1995. It is on the World Health Organization's List of Essential Medicines, which lists the most effective and safe medicines needed in a health system. It is available as a generic medication. The wholesale cost in the developing world is about US$0.28–3.45 per month as of 2015. In the United States, as of 2017, the wholesale cost of a typical dose is $1.13 per month. In 2016, it was the 9th most prescribed medication in the United States, with more than 49 million prescriptions. A version combined with hydrochlorothiazide is available.

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