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Ramipril, sold under the brand name Altace among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. Also used to prevent cardiovascular disease in those at high risk. It is a reasonable initial treatment for high blood pressure. It is taken by mouth.Common side effects include headaches, dizziness, feeling tired, and cough. Serious side effects may include liver problems, angioedema, kidney problems, and high blood potassium. Use in pregnancy and breastfeeding is not recommended. It is an ACE inhibitor and works by decreasing renin-angiotensin-aldosterone system activity.Ramipril was patented in 1981 and approved for medical use in 1989. It is available as a generic medication. A month supply in the United Kingdom costs the NHS less than £1 as of 2019. In the United States, the wholesale cost of this amount is about US$2. In 2016, it was the 153rd most prescribed medication in the United States, with more than 4 million prescriptions.
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