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Xylometazoline, also spelled xylomethazoline, is a medication used to reduce symptoms of nasal congestion, allergic rhinitis, and sinusitis. Use is not recommended for more than seven days. Use is also not recommended in those less than three months of age and some say not less than 6 years of age. It is used directly in the nose as a spray or drops.Side effects include trouble sleeping, irritation of the nose, nausea, and headache. Long term use is not recommended due to a rhinitis medicamentosa when stopped. Use is not recommended during pregnancy. Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication.Xylometazoline was patented in 1956 and came into medical use in 1959. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Xylometazoline is available as a generic medication. The wholesale cost in the developing world is about 0.75 USD for a 10 ml bottle. In the United Kingdom that dose costs the NHS about 2.10 pounds.
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