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Febuxostat

dm+d VMPP - 17030211000001103

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Febuxostat, sold under the brand names Uloric among others, is a medication used long-term to treat gout due to high uric acid levels. It is generally only recommended in those who cannot take allopurinol. When initially started, medications such as NSAIDs are often recommended to prevent gout flares. It is taken by mouth.Common side effects include liver problems, nausea, joint pain, and a rash. Serious side effects include an increased risk of death as compared with allopurinol, Stevens-Johnson syndrome, and anaphylaxis. Use is not recommended during pregnancy or breastfeeding. It inhibits xanthine oxidase, thus reducing production of uric acid in the body.Febuxostat was approved for medical use in the European Union in 2008 and in the United States in 2009. No generic version is available as of 2019, though one has been approved. In the United Kingdom a month of treatment costs the NHS about 24 pounds. In the United States the wholesale cost of a month's worth of medication is about US$320.

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